The quality of 5-aminolevulinic acid-induced photodynamic diagnosis and transurethral resection of bladder tumors: does the urologist play a role?.
نویسندگان
چکیده
INTRODUCTION The aim of this study is to evaluate the quality of photodynamic diagnosis (PDD) and transurethral resection of bladder tumors (TURBT) among different urologists. PATIENTS AND METHODS The selected data consists of 194 patients, 268 5-aminolevulinic acid (5-ALA)-induced PDD procedures and 934 biopsies. Tumors were resected and biopsies were taken from suspicious areas under guidance of white light endoscopy and 5-ALA-induced fluorescence cystoscopy. The quality of PDD was determined by evaluating the mean number of tumors resected by 5 urologists and, thereafter, assessing the time to recurrence between groups. RESULTS Urologist 1 took 37% more biopsies (p < 0.001) and diagnosed 42% more tumors (p = 0.005) and 46% more false positives (p < 0.001) from bladders compared to urologists 2, 3, 4 and 5 together. The mean time to bladder cancer recurrence for all recurrences within 0-18 months was 11.0 months for operator 1 and 8.3 months for the other urologists (p = 0.01). CONCLUSIONS The resecting urologist appears to be an important factor for the quality of standard and PDD-assisted TURBT. Learning curve programs may be required with experienced surgeons accompanying those with less experience.
منابع مشابه
Photodynamic Diagnosis in Urology: State-of-the-Art
no. 1085 presented at the annual American Uro-logical Association congress, May 19–24, 2007, Anaheim,CA. [41] Filbeck T, Roessler W, Knuechel R, Straub M, Kiel HJ,Wieland WF. 5-Aminolevulinic acid-induced fluorescenceendoscopy applied at secondary transurethral resection after conventional resection of primary superficial blad-der tumors. Urology 1999;53:77–81.[42] Grimb...
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ورودعنوان ژورنال:
- Urologia internationalis
دوره 89 3 شماره
صفحات -
تاریخ انتشار 2012